There would be a "zero-tolerance approach" to graffiti, said charity Crimestoppers, as it looked to tackle the "escalating issue" in Northampton.
A four-week campaign has begun to get residents to report cases of the illegal artwork and any information on those responsible, with people able to get in touch anonymously.
It was working with Fearless, its youth service, and West Northamptonshire Council, which has increased the maximum fine for graffiti and other environmental crimes to £500.
"Graffiti is not only an act of vandalism – it undermines community pride, damages both public and private property, and can foster a sense of unease among residents and visitors," the charity said.
The campaign, which says "graffiti is not art, but it is a crime", is being advertised across social media and transport to raise awareness.
It was part of the town's wider regeneration efforts and aimed to protect the visual appeal and community spirit of neighbourhoods, the charity added.
Lydia Patsalides, the East Midlands regional manager for Crimestoppers, said: "Our communities flourish when we come together to tackle the issues that affect us all.
"Graffiti poses a real threat to the quality of life in Northampton.
"We urge anyone who can provide information about graffiti-related activities to come forward."
She reiterated that all reports remained "100% anonymous".
